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precedente: S1.3
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livello superiore: S1
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seguente: S1.5
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S1.4 - Acute concentrations of aqueous Cu result in numerous changes of
structure and function of the polytene chromosomes of chironomid
larvae
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Michailova Paraskeva (1),
Petrova Ninel (2),
Ilkova Julia (1),
Bovero Stefano (3),
Brunetti Stefano (3),
White Keith (4),
Sella Gabriella (3)*
| (1) |
Institute of Zoology, Bulgarian Academy of Sciences, Tzar
Osvoboditel boulevard 1, 1000 Sofia, Bulgaria |
| (2) |
Institute of Zoology, Russian Academy of Sciences, Universitetskaia
1, St. Petersburg 199034, Russia |
| (3) |
Dipart. di Biologia Animale e dell'Uomo, Università degli Studi
di Torino, Via Accademia Albertina 13, 10123 Torino, Italia |
| (4) |
School of Biological Sciences, University of Manchester, Oxford
Road, Manchester M13 9PT, United Kingdom |
| * |
gabriella.sella@unito.it |
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Structural and functional polytene chromosome aberrations were analyzed in
fourth instar larvae of Chironomus riparius hatching from fertilized
eggs which were subject to 48 hours exposure to four concentrations of
aqueous Cu: 0.0 (control), 0.005, 0.01, 0.05 mg/l. All the tested Cu
concentrations induced significantly more structural chromosome aberrations in
treated compared to control larvae according to a dose dependent
relationship. A significantly higher frequency of functional aberrations,
specifically decondensed centromeres and telomeres and reduction in activity
of Balbiani rings, was observed in treated compared to control larvae. By
comparing breakpoints resulting from treatment with chromium and lead from
earlier studies with those Cu-induced many chromosomal breakpoints
particularly vulnerable to trace metals were identified. We also show that
increase in frequency of structural and functional chromosome aberrations is
a more sensitive indicator of acute Cu genotoxicity in chironomid larvae than
changes in external morphology.
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consulta l' Indice analitico (alfabetico per autore) |
sfoglia l' Indice delle sessioni del Congresso |
a cura di Comoglio, Comino, e Bona
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